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Test Methods Overview
IMUGEN utilizes various laboratory test methodologies, each designed and refined to best demonstrate evidence of infection with tick-borne pathogens. Antibody Capture EIA is an enzyme-based test developed to identify various isotypes of the host immune response. Other methodologies to identify specific immune response evidence of infection include Western Immunoblotting (WB) and Immunofluorescence (IFA). Polymerase Chain Reaction (PCR), also referred to as nucleic acid testing, is a very powerful molecular technique that – in contrast to identifying antibodies – directly demonstrates the presence of the pathogen’s specific DNA sequences in an appropriate clinical specimen.
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