Serum and cerebral spinal fluid (CSF) samples are tested quantitatively for IgM, IgG and IgA antibodies to B. burgdorferi using kinetic antibody capture enzyme immunoassays (EIA). The result will include a CSF/serum specific antibody ratio determination for each antibody isotype. The serum sample will also be tested by immunoblots. If the acute specimen is negative (i.e. antibodies undetectable) and the clinical history strongly suggests infection, collect a convalescent specimen 3-4 weeks later.
Specimen Requirements for Lyme Antibody Tests:
Type: Serum and CSF must both be sent
Volume: 2.0 ml of each
Minimum: 0.5 ml of each
Storage: Refrigerate at 2-8°C
Stability: 2 Weeks Refrigerated or Frozen at -20°C
Turnaround Time: Routinely 24 to 48 Hours From Receipt