Serum and CSF samples are tested quantitatively for IgM, IgG and IgA antibodies to B. burgdorferiusing kinetic antibody capture enzyme immunoassays (EIA). The result will include a CSF/serum specific antibody ratio determination for each antibody isotype. The serum sample will also be tested by immunoblots. If the acute specimen is negative (i.e. antibodies undetectable) and the clinical history strongly suggests infection, collect a convalescent specimen 3-4 weeks later.
Specimen Requirements for Lyme Antibody Tests:
Type: Serum or EDTA Plasma and CSF
Volume: 2.0 ml of each
Minimum: 0.5 ml of each
Storage: Refrigerate at 2-8°C
Stability: 5 Days Refrigerated or Frozen at -20°C
Turnaround Time: Routinely 24 to 48 Hours From Receipt